Package Insert

Med Administration Guide

General dosing for 5 to 100+ kg

Weight 41 kg or greater

	Bolus Dose	2nd Dose	3rd Dose
Dose (mg)	150 mg/kg	50 mg/kg	100 mg/kg
Diluent (ml)	200	500	1000
Time (hrs)	1	4	16

Weight 21 to 40 kg

	Bolus Dose	2nd Dose	3rd Dose
Dose (mg)	150 mg/kg	50 mg/kg	100 mg/kg
Diluent (ml)	100	250	500
Time (hrs)	1	4	16

Weight 5 kg to 20 kg

	Bolus Dose	2nd Dose	3rd Dose
Dose (mg)	150 mg/kg	50 mg/kg	100 mg/kg
Diluent (ml)	3 ml/kg	7 ml/kg	14 ml/kg
Time (hrs)	1	4	16

Calculate IV Dose (5 kg up to 100 kg)

Weight (kg): Submit Reset

	Bolus Dose	2nd Dose	3rd Dose
Dose (mg)
Diluent (ml)
Total Volume (ml)
mOsmol/L in SW
mOsmol/L in ½ NS
mOsmol/L in D5W

Verify that mOsmol/L is over 150

Prepare Dose

ACETADOTE must be diluted in sterile water for injection, 0.45% Sodium Chloride or 5% Dextrose.

Dilution in these three solutions results in different osmolarity for each. Be sure that the osmolarity is at least 150 mOsmol/L.

The color of the diluted solution ranges from colorless to slight pink or purple once punctured.

The diluted solution can be stored for 24 hours at room temperature